| Dataset | ranked_basal_vs_classical |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | PHASE I - FUNCTIONALIZATION OF COMPOUNDS%REACTOME DATABASE ID RELEASE 96%211945 |
| Enrichment Score (ES) | -0.63749164 |
| Normalized Enrichment Score (NES) | -1.9357083 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0057041384 |
| FWER p-Value | 0.079 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | CYP24A1 | 70 | 11.151 | 0.0379 | No |
| 2 | CYP4F22 | 111 | 9.742 | 0.0722 | No |
| 3 | ADH7 | 639 | 4.182 | 0.0585 | No |
| 4 | PTGIS | 991 | 3.236 | 0.0511 | No |
| 5 | CYP4B1 | 1480 | 2.430 | 0.0330 | No |
| 6 | ADH5 | 2279 | 1.678 | -0.0052 | No |
| 7 | PTGES3 | 2866 | 1.344 | -0.0328 | No |
| 8 | HSP90AB1 | 2871 | 1.342 | -0.0280 | No |
| 9 | FMO1 | 3347 | 1.122 | -0.0503 | No |
| 10 | CYB5R3 | 3619 | 1.014 | -0.0616 | No |
| 11 | CYP11A1 | 4070 | 0.838 | -0.0835 | No |
| 12 | RXRA | 4358 | 0.747 | -0.0967 | No |
| 13 | CYP19A1 | 4586 | 0.674 | -0.1069 | No |
| 14 | CYP7B1 | 4686 | 0.649 | -0.1099 | No |
| 15 | CYP26B1 | 4943 | 0.583 | -0.1220 | No |
| 16 | AOC2 | 5022 | 0.568 | -0.1242 | No |
| 17 | CYP1B1 | 5795 | 0.396 | -0.1658 | No |
| 18 | CBR3 | 5800 | 0.395 | -0.1645 | No |
| 19 | CYP1A1 | 6247 | 0.316 | -0.1882 | No |
| 20 | AIP | 6382 | 0.295 | -0.1946 | No |
| 21 | CYP4F8 | 6463 | 0.282 | -0.1980 | No |
| 22 | CYP1A2 | 6498 | 0.277 | -0.1988 | No |
| 23 | ADH1B | 6645 | 0.257 | -0.2060 | No |
| 24 | CYP2U1 | 7557 | 0.136 | -0.2563 | No |
| 25 | EPHX1 | 7844 | 0.105 | -0.2719 | No |
| 26 | CYP8B1 | 8175 | 0.074 | -0.2900 | No |
| 27 | AOC3 | 8407 | 0.052 | -0.3027 | No |
| 28 | PTGS1 | 8481 | 0.046 | -0.3066 | No |
| 29 | FDXR | 8565 | 0.037 | -0.3110 | No |
| 30 | ARNT2 | 8665 | 0.027 | -0.3165 | No |
| 31 | CYP2E1 | 8822 | 0.010 | -0.3251 | No |
| 32 | ARNT | 9062 | -0.014 | -0.3384 | No |
| 33 | ALDH1B1 | 9640 | -0.068 | -0.3703 | No |
| 34 | AHRR | 10166 | -0.134 | -0.3991 | No |
| 35 | CYP46A1 | 10180 | -0.135 | -0.3993 | No |
| 36 | CYP2A6 | 10267 | -0.146 | -0.4035 | No |
| 37 | CYP21A2 | 10309 | -0.151 | -0.4053 | No |
| 38 | CYP26A1 | 10454 | -0.170 | -0.4127 | No |
| 39 | POR | 10862 | -0.225 | -0.4345 | No |
| 40 | CYP26C1 | 10935 | -0.236 | -0.4376 | No |
| 41 | POMC | 11031 | -0.250 | -0.4420 | No |
| 42 | AHR | 11795 | -0.379 | -0.4831 | No |
| 43 | NR1H4 | 12050 | -0.427 | -0.4957 | No |
| 44 | CYP7A1 | 12126 | -0.442 | -0.4982 | No |
| 45 | NCOA2 | 12529 | -0.531 | -0.5186 | No |
| 46 | CYP4F11 | 12996 | -0.640 | -0.5422 | No |
| 47 | ADH4 | 13119 | -0.670 | -0.5465 | No |
| 48 | NQO2 | 13184 | -0.686 | -0.5475 | No |
| 49 | PAOX | 13269 | -0.709 | -0.5495 | No |
| 50 | BPHL | 13437 | -0.748 | -0.5560 | No |
| 51 | FDX1 | 13717 | -0.833 | -0.5684 | No |
| 52 | CYB5B | 14169 | -0.988 | -0.5899 | No |
| 53 | CYP4V2 | 14384 | -1.076 | -0.5978 | No |
| 54 | CYP2B6 | 14733 | -1.226 | -0.6126 | No |
| 55 | FMO2 | 14835 | -1.280 | -0.6134 | No |
| 56 | CYP39A1 | 14839 | -1.282 | -0.6088 | No |
| 57 | NCOA1 | 14886 | -1.308 | -0.6064 | No |
| 58 | CYP4A11 | 15005 | -1.370 | -0.6079 | No |
| 59 | CYP51A1 | 15096 | -1.429 | -0.6075 | No |
| 60 | CYP2D6 | 15213 | -1.487 | -0.6084 | No |
| 61 | CYP2A7 | 15261 | -1.512 | -0.6054 | No |
| 62 | CYP27A1 | 15487 | -1.654 | -0.6117 | No |
| 63 | FMO3 | 15551 | -1.702 | -0.6088 | No |
| 64 | CYP4F3 | 15653 | -1.785 | -0.6078 | No |
| 65 | CYP27B1 | 15952 | -2.028 | -0.6168 | No |
| 66 | MAOA | 16026 | -2.100 | -0.6130 | No |
| 67 | MAOB | 16146 | -2.225 | -0.6112 | No |
| 68 | ADH1A | 16479 | -2.660 | -0.6198 | No |
| 69 | CES1 | 16669 | -2.993 | -0.6191 | No |
| 70 | CYP2R1 | 17000 | -3.670 | -0.6237 | Yes |
| 71 | CYP2C18 | 17119 | -3.989 | -0.6153 | Yes |
| 72 | CYP2C8 | 17160 | -4.113 | -0.6021 | Yes |
| 73 | CYP4F12 | 17223 | -4.326 | -0.5894 | Yes |
| 74 | CYP2W1 | 17271 | -4.488 | -0.5752 | Yes |
| 75 | ALDH3A1 | 17318 | -4.661 | -0.5602 | Yes |
| 76 | CYP2J2 | 17400 | -5.010 | -0.5460 | Yes |
| 77 | ALDH1A1 | 17439 | -5.200 | -0.5286 | Yes |
| 78 | CES3 | 17468 | -5.407 | -0.5099 | Yes |
| 79 | CYP2C19 | 17507 | -5.600 | -0.4910 | Yes |
| 80 | TBXAS1 | 17585 | -6.159 | -0.4722 | Yes |
| 81 | CYP2C9 | 17616 | -6.352 | -0.4500 | Yes |
| 82 | AADAC | 17676 | -6.815 | -0.4277 | Yes |
| 83 | ADH6 | 17688 | -6.949 | -0.4023 | Yes |
| 84 | CMBL | 17733 | -7.447 | -0.3768 | Yes |
| 85 | CYP3A4 | 17811 | -8.382 | -0.3496 | Yes |
| 86 | CYP4F2 | 17820 | -8.511 | -0.3182 | Yes |
| 87 | CYP3A5 | 17861 | -9.264 | -0.2856 | Yes |
| 88 | ADH1C | 17873 | -9.662 | -0.2500 | Yes |
| 89 | ACSS2 | 17886 | -10.017 | -0.2131 | Yes |
| 90 | CES2 | 17915 | -10.632 | -0.1748 | Yes |
| 91 | CYP3A7 | 17937 | -11.246 | -0.1338 | Yes |
| 92 | CYP2S1 | 17959 | -12.046 | -0.0898 | Yes |
| 93 | ACSS1 | 17963 | -12.219 | -0.0441 | Yes |
| 94 | ALDH2 | 17969 | -12.724 | 0.0033 | Yes |
